Anti-drug antibodies (ADAs) can compromise drug efficacy and lead to immunogenicity-related adverse effects. Understanding ADA responses is critical for developing safe, effective biotherapeutics.
We provide high-resolution peptide microarray-based ADA epitope mapping, helping researchers identify immunogenic hotspots, pre-existing and drug-related antibody responses, and make date-driven decisions to optimize biotherapeutic design and treatment.
30,000+ epitopes mapped with over 1,000 trusted partners in biotech, pharma, and academia
We understand that getting early and accurate immunogenicity data is crucial for minimizing risks associated with immune adverse effects in biotherapeutic development. Our straightforward epitope mapping approach combines the power of the PEPperCHIP® Peptide Microarray platform with over a decade of scientific expertise:
Analyze linear and conformational epitopes
Identify epitopes at the amino-acid level
Screen multiple targets, isotypes, or samples at once
Get detailed ADA analyses in 6-7 weeks
Interested in learning more about our process and custom solutions?
Project workflow
Talk with our experts to define project goals and specifications
We print your microarray while you send us your samples. When both are ready, we perform the immunoassays.
We analyze your data and send you a detailed sample analysis report
PEPperPRINT's peptide microarrays have been successfully used to analyze ADA responses in different contexts. Read the case study to learn how our technology was used to:
Discover how PEPperPRINT's ADA epitope mapping can streamline your drug development and help improve therapeutic safety. Contact us today to discuss your project and receive a customized quote.
Typically, 100–200 µL per sample is sufficient.
We can analyze mono- and polyclonal antibodies, chimeric proteins, cytokines, viral capsid proteins, and most other proteins as long as their amino acid sequence is known.
We would need your target protein sequence and your sample for analysis
First we do a consultation to discuss the basic details of your project. Knowing the size of your target protein and number of samples helps us plan the experimental setup as well as provide a custom quote for your project. Once approved, we design and print the peptide microarrays for your project. Production takes 4-5 weeks, and during this time you can send us your samples for analysis. We perform the immunoassays as soon as we have both the microarrays and your samples. This is followed by data analysis, which typically takes 1-2 weeks. Afterwards, we email you the full scientific report.
Collaborate seamlessly across devices from wherever you may be – whether you’re in the office, on the go, or making last-minute changes before your next meeting.
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This template is really nice and offers quite a large set of options.
Ive had the pleasure of working with Sprocket Rocket since its inception and find it to be an invaluable tool in helping modernize our HubSpot build process.
This template is really nice and offers quite a large set of options.
Ive had the pleasure of working with Sprocket Rocket since its inception and find it to be an invaluable tool in helping modernize our HubSpot build process.
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