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Discover Novel Autoantibody Targets

Screen over 21,000 folded human proteins in a single experiment to uncover unknown autoantibody targets, accelerate biomarker discovery and de‑risk downstream experiments.

21,000+
Human Proteins
275+
Publications
81%
Proteome Coverage
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Why choose HuProt™ for autoimmune research?

Autoimmune diseases affect millions worldwide, yet many autoantibody targets remain unknown. Traditional approaches are limited in scope, often focusing on predetermined protein panels that may miss critical disease-relevant targets.

Researchers need comprehensive, unbiased screening methods to identify novel autoantibody targets, understand disease mechanisms, and develop better diagnostic biomarkers.

The HuProt™ Human Proteome Microarray v4.0

Comprehensive Coverage

Over 21,000 correctly-folded human proteins covering 81% of the human proteome, ensuring you don't miss important autoantibody targets.

Functional 3D Proteins

GST-purified, properly folded 3D proteins expressed in eukaryotic systems retain native conformation and biological function for accurate binding analysis.

Multiple Sample Types

High signal-to-noise ratios with serum, plasma, CSF, tissue lysates, and other biological samples commonly used in autoimmune research.

Multi-Isotype Detection

Simultaneous analysis of IgG, IgA, IgM, and other antibody isotypes provides comprehensive autoantibody profiling.

Applications in autoimmune research

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Autoantibody Target Discovery

Identify novel autoantibody targets in patients with autoimmune diseases, expanding understanding of disease pathogenesis.

Biomarker Development

Discover diagnostic and prognostic biomarkers for early disease detection and treatment monitoring.

Disease Subtyping

Characterize autoantibody profiles to identify disease subtypes and personalize treatment approaches.

Mechanism Studies

Understand disease mechanisms by mapping autoimmune responses across the human proteome.

Treatment Monitoring

Track changes in autoantibody profiles during treatment to assess therapeutic efficacy.

Cross-Disease Comparison

Compare autoantibody profiles between different autoimmune conditions to identify shared pathways.

Vaccine Development

Identify and monitor autoantibody responses before and after immunization for optimizing vaccine design.

Drug Development

Profile interactions of drug candidates to identify off-target effects and possible adverse anti-drug responses.

Why partner with PEPperPRINT?

Autoimmune Expertise

Extensive experience working with autoimmune samples and understanding the unique challenges of autoantibody research.

Comprehensive Service

Single point of contact from project design to post-experiment reporting, ensuring full data transparency.

Quality and Compliance

ISO 9001-certified quality management and standard protocols ensure reliable, reproducible results.

Ready to discover new targets?

Let our experts help you design the perfect HuProt™ study for your autoimmune research.

✓ Project consultation and study design

✓  Sample preparation guidance

✓  Comprehensive data analysis

✓  Expert interpretation and reporting

Additional resources

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HuProt v4.0 Full Content 

Annotated protein list
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Featured customer publication

Moritz et al. 2025
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Application Flyer

Protein and Peptide Microarray Solutions
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